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Millman Team Real Estate

$1,248,000
3 Bed
4 Bath
1,630 Sqft
0.08 Acre Lot

643 Grand Avenue, South San Francisco, California 94080

  • Residential Property Type
  • 1,630 Sqft Square Footage
  • 1895 Year Built
Property Description

Ideally located near Downtown South San Francisco and the cities thriving biotech and life-sciences corridor, 643 Grand Avenue where space, comfort, and a remarkable garden setting come together in the heart of South San Francisco. 643 Grand Avenue offers a spacious and versatile layout with excellent access to major transportation and employment centers. The home features 3 bedrooms and 4 bathrooms, with a private full bathroom for each bedroom. Additional highlights include high ceilings, abundant natural light, hardwood floors, a full basement with ample storage, and a detached 2-car garage equipped with a 220-volt outlet for EV charging. The home also features a water purification system, tankless water heater, and water softener. The quaint lot includes a freshly manicured organic vegetable garden with sunflowers and offers potential for an ADU. Conveniently located near Downtown South San Francisco, Genentech, Caltrain, US-101, and I-280.

Basic Details
Residential
For Sale
ML82059314
$1,248,000
3
4
1,630 Sqft
1895
0.08 Acre
Active
4
Single Family Residence
: Shingle
Features
: Central
: None
: Public Sewer
: Skylight(s)
$0
Address Map
CA
San Mateo
South San Francisco
94080
Grand
643
Avenue
W123° 34' 42.6''
N37° 39' 26.5''
Cross Street: Orange Avenue
699 - Not Defined
RM0000
Neighborhood
South San Francisco Unified
Additional Information
$0
$0
$0
$0
$0
: Slab
2.0
2026-08-27
2
: Public
Broker/Agent Information
Christie's International Real Estate Sereno
Jill Penna
Listing Information
ML5085880
ML5033630
Active
2026-09-03T07:50:46Z
CRMLS
: Standard
2026-08-27T16:30:54Z
Agent info
Ray Millman
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